Dr. James O'Keefe on Cardiovascular impacts of extreme endurance exercise

Core perspective shared by Dr. James O'Keefe (University of Missouri-Kansas City): "The U-Shaped Curve of Exercise: Moderate aerobic exercise dramatically reduces mortality, whereas excessive chronic ultra-endurance training can promote myocardial fibrosis." Key Works: Mayo Clinic Proceedings on Chronic Extreme Endurance Exercise (2012), The Omega-3 Index in Cardiology.