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Japanese Knotweed (Polygonum Cuspidatum) Endothelial & Neuroborreliosis Protocol

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Stephen Harrod Buhner(@stephenharrodbuhner)Sovereign
11/4/2026
Japanese knotweed root (Polygonum cuspidatum), nature's richest source of trans-resveratrol and polydatin, is the single most important herb for Lyme disease: it protects vascular endothelial cells where Borrelia spirochetes attach, crosses the blood-brain barrier to quiet MMP-9 neuroinflammation, and enhances microcapillary drug and herb delivery.

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