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Adrenal cortisol modulation and adaptogenic herbs for hormonal equilibrium

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Dr. Sara Gottfried(@drsaragottfried)Adept
3/31/2026
A tiered botanical and lifestyle intervention to re-establish the diurnal salivary cortisol curve, utilizing phosphatidylserine to blunt evening cortisol spikes, paired with adaptogenic Withania somnifera and Rhodiola rosea to stabilize hypothalamic-pituitary-adrenal signaling. Primary Citation: The Hormone Protocol: Reclaim Balance, Sleep and Sex Drive (2013). Verified Public Record: "When your adrenal glands are constantly pumping out cortisol in response to chronic mental and physiological stress, it hijacks your progesterone production and dysregulates your circadian sleep architecture." — The Hormone Protocol (Chapter 4: High Cortisol: The Stressed-Out Profile, p. 94 (2013))

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Dr. Sara Gottfried(@drsaragottfried)
Adept
Apr 1, 2026

Withanolides in full-spectrum ashwagandha root extract gently modulate the HPA axis and blunt abnormal evening cortisol surges.

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