Dr. David Perlmutter
MD, FACN (Board-Certified Neurologist) — Perlmutter Health Center. Focusing on neurological resilience, gut-brain axis, uric acid control, ketone metabolic fuel. Author of Grain Brain (2013), Brain Maker (2015).
Submitted Protocols
Quercetin Bioflavonoid for Uric Acid Suppression & Vascular Tone
Verified Public Record: "Quercetin acts as a natural botanical modulator of xanthine oxidase, helping maintain serum uric acid below 5.5 mg/dL to protect cerebral blood vessels and clear neuro-inflammatory brain fog." — Dr. David Perlmutter (Drop Acid: The Surprising New Science of Uric Acid, Chapter 6: Lowering Uric Acid with Quercetin and Luteolin, p. 145 (2022))
Curcumin Brain Bioavailability Protocol for Microglial Quenching
Verified Public Record: "Bioavailable curcumin crosses the blood-brain barrier to activate Nrf2 antioxidant pathways, calm hyper-reactive microglial cells, and upregulate Brain-Derived Neurotrophic Factor (BDNF)." — Dr. David Perlmutter (Grain Brain & Brain Maker, Chapter 10: Epigenetic Neuroprotection with Curcumin & DHA, p. 212 (2013))
Standardized Ginkgo Flavone Glycosides for Cerebral Capillary Flow
Verified Public Record: "Standardized Ginkgo biloba leaf extract delivers flavone glycosides and terpene lactones that promote cerebral microcapillary perfusion and shield neuronal membranes from oxidative free radicals." — Dr. David Perlmutter (The Better Brain Book, Chapter 9: Brain-Boosting Botanicals - Ginkgo Biloba, p. 188 (2004))
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Ketone Neuro-Support & Uric Acid Modulation Protocol
Lowering dietary fructose and refined purines to keep serum uric acid strictly below 5.5 mg/dL while elevating circulating beta-hydroxybutyrate (BHB) to provide alternative mitochondrial fuel for cerebral neurons.
Dr. David Perlmutter: Signature Wellness Protocol
Ketogenic neuro-protection and uric acid reduction via quercetin, luteolin, and carbohydrate restriction Primary Focus: Neurological resilience, gut-brain axis, uric acid control, ketone metabolic fuel. Key Works: Grain Brain (2013); Brain Maker (2015); Drop Acid (2022).
Recent Threads
Quercetin Bioflavonoid for Uric Acid Suppression & Vascular Tone: Clinical Notes & Guidelines
26d ago"Quercetin acts as a natural botanical modulator of xanthine oxidase, helping maintain serum uric acid below 5.5 mg/dL to protect cerebral blood vessels and clear neuro-inflammatory brain fog." Citation: Drop Acid: The Surprising New Science of Uric Acid — Chapter 6: Lowering Uric Acid with Quercetin and Luteolin, p. 145 (2022)
Curcumin Brain Bioavailability Protocol for Microglial Quenching: Clinical Notes & Guidelines
26d ago"Bioavailable curcumin crosses the blood-brain barrier to activate Nrf2 antioxidant pathways, calm hyper-reactive microglial cells, and upregulate Brain-Derived Neurotrophic Factor (BDNF)." Citation: Grain Brain & Brain Maker — Chapter 10: Epigenetic Neuroprotection with Curcumin & DHA, p. 212 (2013)
Standardized Ginkgo Flavone Glycosides for Cerebral Capillary Flow: Clinical Notes & Guidelines
26d ago"Standardized Ginkgo biloba leaf extract delivers flavone glycosides and terpene lactones that promote cerebral microcapillary perfusion and shield neuronal membranes from oxidative free radicals." Citation: The Better Brain Book — Chapter 9: Brain-Boosting Botanicals - Ginkgo Biloba, p. 188 (2004)
View 2 MoreShow Less
Ketone neuro-support and the hidden metabolic impact of high uric acid
9mo agoLowering dietary fructose and refined purines to keep serum uric acid strictly below 5.5 mg/dL while elevating circulating beta-hydroxybutyrate (BHB) to provide alternative mitochondrial fuel for cerebral neurons. Primary Citation: Grain Brain: The Surprising Truth About Wheat, Carbs, and Sugar - Your Brain's Silent Killers (2013). Verified Public Record: "High serum uric acid is not merely a marker for gout; it is an evolutionary metabolic survival switch that signals the liver to produce visceral fat, raise blood pressure, and inflame the blood-brain barrier." — Drop Acid: The Surprising New Science of Uric Acid (Chapter 1: The Molecular Alarm Bell, p. 23 (2022))
Dr. David Perlmutter on Neurological resilience
11mo agoCore perspective shared by Dr. David Perlmutter (Perlmutter Health Center): "Ketogenic neuro-protection and uric acid reduction via quercetin, luteolin, and carbohydrate restriction" Key Works: Grain Brain (2013), Brain Maker (2015), Drop Acid (2022).
Recent Comments
""Quercetin acts as a natural botanical modulator of xanthine oxidase, helping maintain serum uric acid below 5.5 mg/dL to protect cerebral blood vessels and clear neuro-inflammatory brain fog." — Verified Citation: Drop Acid: The Surprising New Science of Uric Acid (Chapter 6: Lowering Uric Acid with Quercetin and Luteolin, p. 145 (2022))"
""Bioavailable curcumin crosses the blood-brain barrier to activate Nrf2 antioxidant pathways, calm hyper-reactive microglial cells, and upregulate Brain-Derived Neurotrophic Factor (BDNF)." — Verified Citation: Grain Brain & Brain Maker (Chapter 10: Epigenetic Neuroprotection with Curcumin & DHA, p. 212 (2013))"
""Standardized Ginkgo biloba leaf extract delivers flavone glycosides and terpene lactones that promote cerebral microcapillary perfusion and shield neuronal membranes from oxidative free radicals." — Verified Citation: The Better Brain Book (Chapter 9: Brain-Boosting Botanicals - Ginkgo Biloba, p. 188 (2004))"